NO & YES
If depends on the equipment reading the shunt's output. Most displays are limited to either a specific current/mv rating or a few specific current ranges all. @ the same mv rating.
If the display is programmable (Arduino, Pi, etc) or has a shunt profile setting matrix, then yes.
A 75nv 100 amp shunt develops a 75mv voltage drop @ 100 amps current flow. 75/100=750uv per amp.
A 50nv 100 amp shunt develops a 50mv voltage drop @ 100 amps current flow. 50/100=500uv per amp.
Without adjustment the meter will read 40% low with the 50mv shunt.
Deltec markets hi quality stunts in several amp to mv ratios. I prefer them for my DIY Arduino protects. More $$$ though.