Half-cell panels are essentially a mini 1S2P array, so I suppose an optimizer apply Vmp to both half-panels and if one half-panel is delivering next to nothing due to shading, the optimizer could take 1/2 Isc @ Vmp and convert it to Isc @ 1/2 Vmp for output into a series string.Lot of very interesting discussion and links in here so far - but I havent seen (or I missed it) any mention of using optimizers like Tigo's. It would remove any shading and voltage variability issues. And it's rapid shutdown capable and easy to implement. Each Tigo TS4-O optimizer runs about $50 US and will work with any inverter or MPPT controller.
Also, it gives you panel-level monitoring so if you ever lose a diode or a panel goes dead you'll know about it immediately.
Still not convinced it’s worth the premium, but the right 1kW product combined with RSD for 2 450W panels in series might be worth looking into...