You could do it that way. Each 4P2S is 46A (11.61 x 4) and 100V (50V x 2). Putting two 4P2S in series with another would be 200V, 92A which gets you up in wire size. You would be better served with 4S2P in each string to keep amps down, that does require 4 PV circuits as I stated. You could Y them (two 4S2P in parallel, total of 16 panels) , that would be 46A in between the Y on each end, probably take 6 ga or larger wire, dependent on length.
I was thinking incorrectly in the above post with the 11A, it would be 23A per PV input. I did have 4 PV circuits to the inverters, was thinking of 8 panels per PV input and forgot about the 2P.
Considering you have various angles and orientations of strings across the roof, you might be better served with 4S2P on the strings (50V x 4= 200V) and 23A per string) and feed each 4S2P to a PV input. Wire size of 10 or 8 ga depending on length. It all depends on what length you run and how you want to run it. In my case, PV goes underground to the house from a ground mount in buried conduit, each string is 13A so the Y makes more sense with 4 strings. Considering you have various lengths from each PV string, it might be just as easy and cheaper to run each string separate.